CBD vs THC: What’s The Difference?

Humans have used cannabis for thousands of years. In countries like India, people have used cannabis not only for its health benefits but even in religious ceremonies. For example, cannabis-infused drinks are traditionally served at some festivals.

Similarly, Europe has used cannabis for various purposes. It grew hemp widely for its fibre. Its cannabis plant or hemp fibre made sailing possible, as early sails were of textile created using hemp fibre.

Similarly, people in various cultures widely consumed cold-pressed hemp seed oil.

However, things suddenly changed in the late 19th century and early 20th century, when different countries introduced a complete ban on cannabis use. For 80-90 years, cannabis was grown only in small amounts, and its cultivation required a special licence. As a result, people stopped using cannabis for good health. Although, illegal cannabis use continued to flourish.

Researchers now understand that banning all kinds of cannabis products or use was one of the biggest mistakes. Science knows that cannabis has some incredible health benefits. Studies show that most health benefits of the cannabis plant are due to cannabidiol (CBD) and other cannabinoids.

It is now evident that most of the ill effects of cannabis were associated with the use of high tetrahydrocannabinol (THC) cannabis strains. THC is the substance or organic compound in cannabis that causes a high. Thus, if people use cannabis extract responsibly, its benefits outnumber health risks.

CBD vs THC

What’s The Difference Between THC and CBD?

The cannabis plant contains more than 500 known phytocompounds; out of them, more than 100 are cannabinoids. Additionally, it has more than 100 terpenes and many other beneficial phytocompounds.

Studies of various phytocompounds identified in the cannabis plant show that almost all are highly beneficial for health. In addition, they might help manage a range of health conditions.

It is amazing to note that some of the cannabinoids in the plant may even have the opposite effect. However, researchers think they have only discovered the tip of the iceberg, and there is still much to learn about the plant.

THC and CBD are the two most discussed cannabinoids in the cannabis plant. They do share some traits; however, they are pretty different.

Studies show that cannabis causes euphoria or a high due to its content of THC. It is the substance that stimulates the part of the brain known to generate pleasure. In addition, it stimulates the reward pathway and strengthens the memories related to various pleasures. Hence, it not only alters mental alertness but is also highly addictive, too.

CBD is the most abundant cannabinoid in the plant. Fortunately, it is also one of the most studied of all cannabinoids. Most health benefits of cannabis or hemp plant are associated with CBD.

Since CBD is responsible for most health benefits, it is common to isolate this compound for health benefits. That is why people use CBD oil, gummies, tinctures, capsules, topicals, and edibles for health benefits.

What Is THC?

THC or tetrahydrocannabinol is the primary psychoactive compound in the cannabis plant, causing high. It is addictive, and its prolonged use may cause more harm than good.

Here it is vital to understand that THC is also a cannabinoid and may benefit health in minute dosages. Thus, regulations allow CBD products with 0.2% THC.

However, at higher dosages, it would cause more harm than good. At higher dosages, it is more like any other street drug that is addictive, harmful to health, reduces mental alertness, increases the risk of violence, motor accidents, and so on.

What Is CBD?

CBD or cannabidiol is a highly beneficial compound. Most of the health benefits of cannabis or hemp are due to its content of CBD. It is mildly psychoactive, as it helps relax and reduce anxiety and pain sensations. However, it does not alter mental alertness at usual dosages. Thus, it is even safe to dry or operate machinery after using CBD.

Health experts are still discovering its health benefits. For example, in recent years, there has been much focus on its ability to reduce epileptic seizures, reduce spasticity in neurodegenerative disorders, and more.

It is suitable for metabolic health, as it can modulate appetite, reduce inflammation, alter immune responses, and more.

What’s The Difference Between CBD and THC?

The main difference between the two is in their psychoactive properties. CBD has a mild relaxing effect on the brain, even at high dosages. However, THC can cause high or euphoria, completely alter mental alertness, and influence body movements or motor function.

It means that at high dosages, THC is quite different from CBD. Although, in minute dosages, it may have health benefits similar to CBD.

Therefore, in the EU, any CBD products must not contain more than 0.2% THC, whereas, in the US, this upper limit is 0.3%.

Additionally, it is worth understanding that THC ingestion would result in a positive drug test. However, ingesting CBD isolate would not result in a positive drug test.

Does CBD Oil Need THC To Work?

The answer to this question is “Yes” and “No”. THC can influence the working of CBD and can boost its certain health effects. However, CBD also works quite well when used alone and thus does not require THC to work.

THC is one of the cannabinoids; thus, even small amounts of THC in CBD oil may result in the entourage effect. In addition, THC-containing CBD oil may help manage muscle spasticity, insomnia, and low appetite.

However, considering the poor safety profile of THC, it is a good idea to use CBD oil without THC. CBD would work quite well without THC and does not require it at all to work. Thus, CBD alone is sufficient to reduce inflammation, seizures, depression, improve gut health, help with migraine, and much more.

CBD and THC

What Are the Benefits of CBD Oil Without THC?

Although THC may boost certain activities of CBD oil, but it is better without it. It is now proven beyond doubt that THC, on prolonged use, may cause more harm than good. Below are some of the health benefits of CBD without THC:

Better safety profile

CBD oil that is THC-free has a much better safety profile. It will not cause addiction, euphoria, or other severe issues. THC-free CBD oil may also have lower toxicity and would not influence other organs like the liver.

Does not cause high

This is the number one reason for preferring THC-free CBD oil. Cannabis causes high due to its content of THC. CBD isolate does not cause high and has no adverse impact on brain health. This is because it will not influence reward pathways like THC.

Does not increase appetite

It is no secret that marijuana increases appetite. However, CBD helps with weight loss. Therefore, it seems that THC is rather an appetite stimulant.

Would not result in a positive drug test

When testing for drug use, that is, for marijuana use, doctors look for TCH levels in the blood. Thus, even minute amounts of THC in CBD oil may result in a positive blood test. However, CBD oil that is THC-free would not result in a positive blood test.

Easier to get regulatory approval

Finally, THC-free means fewer issues in getting regulatory approval. Most health authorities are wary of THC. They know that prolonged THC use may harm health and is also a substance of abuse. If CBD oil is THC-free, getting regulatory approval would be much easier.

To sum up, cannabis or hemp plant contains many cannabinoids. Among them, CBD and THC are most well researched and have quite different health effects. Therefore, although THC may benefit health in small amounts, using THC-free products is a better option. On the other hand, CBD is still quite potent without THC and is suitable for prolonged use.

If you are looking for THC-free CBD products, we have a range of products. We offer CBD wholesale, white label CBD, private label CBD, and more. We are among the reputed CBD manufacturers in Europe.

When should I take CBD?

People are taking CBD in all imaginable manners like oral spray, CBD oil, gummies, CBD-infused foods, vaping, and more. Yet, it appears that the reply to one of the most straightforward questions is missing: when should a person take CBD?

What is the best time to take CBD? How many times should one take CBD? Can one take CBD by food, or not? What is the perfect CBD dosage? There are many such questions.

One of the issues is that information on various online platforms varies significantly. Thus, the more you read, the more confused you get. Hence, this article tries to put an end to all this confusion by exploring what science is saying.

How you take CBD matters

One of the reasons for such confusion is that CBD’s pharmacokinetics is not fully understood yet. After all, it is a food supplement and not a pharmacological drug. However, people tend to use it to manage health conditions.

The most important thing to know first is bioavailability. It means how much CBD will enter the blood circulation after its intake. Products with low bioavailability will only work if taken at a higher dosage so that a sufficient amount enters circulation.

The bioavailability of oral CBD (ingested) is just about 6%. However, bioavailability is high if it is taken sublingually. For example, the bioavailability of oral mucosal spray and vapes could be as high as 31%. It means that the dosage of oral CBD products must be higher than vapes.

However, things do not end here. It seems that products with higher bioavailability like vapes and oral mucosal sprays have a shorter half-life of 10-15 hours. In comparison, oral CBD has a longer half-life of 1-2 days.

Half-life is the time after which half of the CBD that entered the circulation has left it.

Understanding half-life is essential to know when to take CBD, whereas bioavailability shows how much to take and how to take it.

Just take an example of oral CBD, which has quite a low bioavailability, but a long half-life. It means that on the first dose of oral CBD, only a small amount will enter the body. However, it also means that much of it will remain in the body even the next day. Thus, when you take the second and third dose, it results in the accumulation of CBD in the body and, therefore, its higher plasma levels.

when to take cbd

Is There an Ideal Time of Day to Be Taking CBD?

The ideal time to take CBD would depend on the intake route and why someone is using CBD.

CBD accumulates in the body and reaches a peak and consistent plasma level after 4-5 days. It means that after a week of use, the time of taking CBD does not matter much if one is using it for chronic health conditions like improving metabolism, chronic pains, stress, and so on. So important is just to keep taking CBD regularly at a fixed time of the day.

However, besides bioavailability, there is another thing like peak plasma level. It means that after taking CBD, its level increases significantly in the blood for a few hours. Therefore, it means that after its intake, it may help better for the next few hours.

This means that intake time matters when using CBD for acute conditions or something that affects at a particular time. For example, taking CBD in the morning may help reduce stress and anxiety during the day and help normalize blood pressure.

Similarly, taking CBD in the evening may be better for improving the quality of sleep. It may also be good for those who experience evening pains and other issues.

What Some Common Reasons for Taking CBD?

CBD has widespread health benefits, and thus people may use it for a range of health conditions. CBD is not a medication; thus, it is not used to treat or cure health conditions. However, when used along with treatment, it may help. It is also good for preventing certain health conditions.

People are more likely to use CBD for:

  • Managing stress and anxiety
  • Chronic pains of various origins
  • Improving brain and nerve health
  • Managing mental health disorders
  • Seizures control
  • Enhancing sleep quality
  • Normalizing metabolism
  • Managing mood swings
  • Managing substance withdrawal syndrome
  • Improving skin health, especially preventing acne as it has sebostatic action
  • Good for heart health
  • Countering inflammation

CBD Dosage Chart: How Much Should You Take?

The optimal dosage of CBD is not established. Moreover, there are massive individual differences, with some experiencing benefits at the lower dosage while others require higher dosages. Thus, the advice is to start with a minimal dosage and then increase it gradually.

Food and Standards Agency (FSA) UK recommends not exceeding a dose of 70 mg daily, which is about 28 drops of 5% CBD.

Below is the recommendation for getting started with CBD;

  • Start taking 2.5 mg to 5 mg twice daily for a week
  • After one week, switch to a maintenance dose of 5 to 10 mg once a day
  • If it does not help sufficiently, gradually increase the quantity weekly, like by 5 mg weekly. However, do not exceed 70 mg a day.

best time to take cbd

How Often Should You Use CBD?

As mentioned above, starting with a twice-daily dosage is a good idea. However, after a week, CBD achieves a stable plasma level, and thus one can continue with a once-daily dosage. The timing of a once-daily dosage would depend on the health condition. For some, it would be better to take it in the morning, while for others in the evening.

When Should I Take CBD?

When you are getting started with CBD, it is better to take it twice daily. Once in the morning and once in the evening. This will provide you 24 hours relief.

However, after a week, CBD accumulates in the body, and one can continue with a single dose a day. Therefore, if one wants relief for some health issue during the day, it is better to use CBD in the morning. However, better use CBD in the evening for relaxation and improving sleep quality.

Also, avoid taking it with food, as it may interfere with absorption. Thus, either take 30 minutes before a substantial meal or one hour after it.

Summary

CBD may not have such a high bioavailability, but it has a long half-life. It means one needs to take it continually for a week to experience its benefits. Generally, when a person takes it, it does not matter much. However, in some cases, it may play a role. Thus, if one experiences symptoms during the day, better take CBD in the morning. However, take it in the evening to relax and improve sleep quality.

If you are into the CBD business and want to know where to source high-quality CBD products, contact us. We are among the best CBD manufacturers in Europe.

The Best CBD Payment Processors in 2022

So, you have probably done many studies about CBD and are interested in getting started. Most likely, you know where to source the products and how to meet the country’s regulatory requirements.

The next logical step would be micro-business planning. It would be about deciding where to sell, how to sell, setting up the sales platform, and more.

Many would like to have a dedicated online store for their products. However, it is generally not very challenging, as setting up an online store using different platforms is pretty simple and does not cost much. There are many options here, from WooCommerce to Shopify, and all are pretty simple ways of getting started.

However, when people start setting up the online store, many may suddenly hit the wall as they realize that most payment processors are not ready to accept payments for CBD products. It is true that CBD is legal. Nonetheless, regulations are still evolving.

In addition, many payment processing services consider CBD business as a high-risk business, quite like pornography, dating, or online gambling. Thus, they are not ready to manage payments of CBD companies.

The payment processor is a third party, a financial institute, that can process or accept payments via various means like debit and credit cards. Then, after taking their small commission or service charges, they transfer the rest of the amount into your business account.

payment processing

How To Choose a CBD Payment Processor?

As mentioned, most payment processing gateways still regard CBD as a high-risk business. It is true that CBD is now entirely legal in most parts of the world. However, the problem is with the continually changing legal environment.

Some of the reputed payment processors worry that they might also get into trouble for not following specific regulations. Thus, they prefer to stay away from high-risk businesses like CBD, pharmaceuticals, online dating, or gambling.

The problem is not only in the unclear legal framework or regulatory hurdles, but experience shows that people buying such products are also more likely to engage in fraudulent activities.

Thus, not every payment processing company would be ready to work with CBD merchants. However, here are some things to know when opening a merchant account with payment processing companies.

Must be ready to process high-risk transactions

When you start your business, make clear to the payment processing company that they are ready to process CBD-related transactions. Generally, these are companies with much experience in processing high-risk transactions and experience working with websites that provide services like online dating, gaming, travel services, and more.

Here it is vital, to be honest about your products. The Internet is full of information when someone working with low-risk products like selling gift cards also decided to start selling CBD products. And suddenly, they realized that their account got suspended as their payment processing company would not work with CBD products.

Easy to integrate with common platforms

Once you have found the right kind of company that is ready to work with CBD products, another thing to look at is that their services must be easy to integrate with the most common platforms.

So, let’s say that if you have a WordPress website with a WooCommerce store, then the software solution provided by the company must be easy to set up and should not pose any challenges. Otherwise, you may need to spend lots of money on setup costs and may also experience frequent problems.

POS availability

This factor only counts if you are planning to have an offline store. In such a case, you would also need POS system integration. Though most payment processing companies may provide this service, however pay extra attention to the quality of software, ease of use, and reporting functions. Therefore, even if you are not planning to have an offline store, it is good to have a payment processor that provides this option, just in case your plans change in the future.

Low transaction fees

Let’s be honest, most payment processors working with high-risk businesses have higher fees. For example, they may charge a hefty upfront fee and massive commissions for processing every transaction. Thus, try to learn about all the service fees, including setup, statement, terminal, monthly or annual charges, and more.

Of course, it is also essential to understand how they charge a fee. Generally, most good payment processing companies would just deduct a small percentage from each transaction. This is quite a convenient option for beginners, as you are paying from the profit and not out of pocket.

Does PayPal Process CBD Payments?

No, PayPal does not handle CBD payments. If you have other stores and have been working with PayPal, be very clear about it.

There are many cases when people did not know about it, just because they have been working for PayPal for so long and have been using PayPal as a payment processor for years. But, when they started selling CBD products, they got into trouble.

Using PayPal for CBD may result in account suspension, or the company may hold funds for a large amount of time. For example, there are reports when PayPal held the funds for six months or more!

CBD payment

Are There Any High-Risk Payment Processors for CBD?

Yes, there are many. Things are now much better than they used to be even a decade back. There is not considerable competition in the financial sector. Thus, tens of companies, banks, and other organizations provide payment processing services. Therefore, one must carefully understand the pros and cons of each payment processing company.

Which Is the Best CBD Payment Processor for Me?

Though there are many payment processors, here are a few of the better ones known to work with CBD sellers.

USAePay

One of the oldest payment processing companies was founded way back in 1988 and thus has been in the business from quite an early day of eCommerce. Over the years, their tools have become much better and easy to integrate with many custom features. They also provide excellent customer support. The only downside is that they might be a bit slow to respond to queries.

NMI

It is quite a dynamic and fast-growing company, with many reputed customers. Therefore, they are a good choice for more extensive platforms as they have excellent experience in handling large clients. Moreover, they support different kinds of credit and debit cards. However, on the downside, they have a small monthly fee for their services, which is apart from a small fee per transaction.

PayKings

It is a company that prides itself as a provider of high-risk merchant accounts. They are ready to work with different industries, from porn, and gaming, to CBD, without any issues. For them working with regulated products like CBD is not an issue. It means that they have a fast account approval process.

Easy Pay Direct

Last but the most reputed payment processor in this list is Easy Pay Direct. It is quite an old company, established in the year 2000. They have experience in working with both high-risk clients and large, well-established eCommerce stores. They are handling the business transactions of many reputed CBD companies.

Thus, Easy Pay Direct has quite a good software solution that can handle all kinds of transactions with almost zero complaints. They have one of the best payment gateways in the industry. However, it also means that they have some setup fees and descent monthly fees, along with high processing rates.

Surely, the above list is not comprehensive, and many more payment processors can work with the CBD industry. Moreover, the CBD industry is not risky compared to online gaming, dating websites, etc. Therefore, though most of them would be able to handle financial transactions securely, nonetheless, one should choose any payment processors after due diligence.

If you have any questions regarding payment processing for CBD products, we would be glad to help you with it.

The Key Challenges of Owning a CBD Business in 2022

CBD is already a big thing, and it will become even bigger. Experts estimate that the global CBD market is bigger than 5 billion USD. But, that is not all. It is a market that is bound to grow at an excellent pace for the next decade or more. Thus, it is expected to grow at the rate of 15-20% each year, which is a very high growth rate.

However, again, that is not all to the story. After all, the size of the market or its growth rate does not provide a complete picture. What is good about CBD is the massive profit margins. When compared to other health supplements, one can still sell CBD products at a premium price.

There are many growth drivers of CBD sales. It is worth understanding that still the majority of the world population still has to explore the benefits of CBD products. Another excellent thing about CBD is that it can be added to just any product from foods, supplements, or cosmetics. And thus, the possibilities are almost endless.

Moreover, the covid-19 pandemic has only positively influenced the CBD market. It is because now, more and more people are looking for natural remedies to stay healthy and safe.

Many people wonder if it is the right time to enter the CBD business or if it is not too late?

First and foremost, it is never too late to enter any business. However, one needs to create the right kind of business strategy depending on the market trends. For example, marketing strategy in countries where CBD products are just starting to take off would differ considerably from more mature markets.

CBD business challenges

How To Start Up a CBD Business

It could not be easy for those inexperienced in the health supplements business to understand a few things. However, first and foremost, one must know that the healthcare products market is more regulated than some other products.

Thus, the starting point for CBD business should be exploring the legal regulations regarding CBD products in the nation. For example, in the EU, CBD oil is considered to be a novel food, and thus one must get CBD oil registered as a novel food with health authorities or the European Commission. However, laws in other countries may vary greatly, and some nations are yet to legalize CBD.

Additionally, one should also understand other laws regulating the food products, packing, advertising of the healthcare and food products, and more.

Once the person has fully understood the legal requirement for getting started, the next step should be deciding on the product profile. First, one must determine what kind of segment to enter, like CBD oil, CBD-infused foods, CBD cosmetics, hemp oil products, and more.

Once a person has taken a decision about entering the specific CBD segment, let’s say CBD products for physically active individuals, sports people, products helping them stay focused and train better. First, one would need to think about differentiating the product from competitors. This may is done in many ways, like adding different ingredients to the product.

Next, one should decide on sales channels and product promotion. For example, some may choose to sell their product through Amazon, while others do so through a dedicated Shopify store or WooCommerce store. Finally, depending on the choice of platform, one would need to come up with a product promotion plan.

CBD business and challenges

The Top 3 Challenges CBD Business Owners Face

Starting any business is never going to be a straightforward task. Therefore, initial plans require frequent reassessment and changes. This is especially true for relatively more regulated businesses like food supplements, medications, or novel foods. Below are some of the challenges most CBD business owners face.

Challenging Public Perceptions of CBD

It is true that CBD seems to be everywhere and in everything. But, nonetheless, there are still many people who know almost nothing about CBD. Even worse, they still think that since CBD is from the cannabis plant, it means that it retains some properties of marijuana. Thus, they often consider it as something addictive and harmful to health.

There are many ways to overcome these issues, like sponsoring more clinical research into the subject and sharing scientific information with clients. It also means creating the right kind of promotional campaigns that help clients learn more about CBD.

Dealing With the Legality of CBD in Different Countries

This may often turn out to be the biggest challenge to overcome. Many CBD businesses never turn into reality, as startups find it too difficult to overcome regulatory hurdles. In countries like the US, things may seem pretty straightforward. Nonetheless, laws differ in every state.

Similarly, in the EU, edible CBD products must now get novel food approval, which is quite a tedious process. It means preparing a massive dossier, going through lots of documentation, and investing time and money to get the approval.

Additionally, there are significant differences between how various laws are implemented and interpreted in various nations. For example, some may allow the import of CBD products but not allow their retail sale through online platforms.

Navigating eCommerce Challenges of Selling CBD Online

These days most of the sales come through online platforms, and brick and mortar stores contribute little to the overall sales of CBD products. Moreover, distributing products to traditional stores is quite challenging for a new business. Thus, the best way to sell their products is through e-commerce platforms for new businesses.

However, most people find it quite challenging to get started with eCommerce. Making products available on any online platform is one thing, but a much greater challenge is sales generation. Here the ways of product promotion are almost endless, from Google Ads to social media marketing. All these things are easy said than done. Online advertising requires the allocation of massive resources and prolonged effort to achieve any considerable sales.

Final thoughts

Getting started with the CBD business indeed requires much learning, but it is true for just any business. Thus, these challenges should not be a cause for canceling the business plans. Instead, it only demonstrates the value of proper planning. Additionally, one can readily overcome many of these challenges by finding the right business partner who can help you get started.

CBD in Functional Foods: A Guide

Cannabidiol (CBD) is one of the more than 100 cannabinoids in the cannabis plant. However, CBD is most popular, as it is most abundant in the plant, readily extractable, and is well studied by science. In addition, CBD has completely changed the way people perceive the cannabis plant. Now, they associate this plant with health benefits rather than substance abuse.

What is incredible about cannabinoids is that they have many different functions. Sometimes, various cannabinoids work in synergy with each other, and other times in an opposite way. Since CBD has so many health effects, it is surely a time to include it in a regular diet to recognize it as one of the most potent functional foods.

There are other reasons why It is necessary to start exploring CBD as a functional food. These days, 70% of all clinical conditions are non-infectious chronic ailments. One of the problems with chronic disorders is that they are difficult to treat with medications and cause significant pain and disability.

Just take an example of obesity, diabetes, hypertension, dementia, joint pains, lower back pain, and more. Most of these conditions are lifelong, or they tend to reoccur.

Studies show that most chronic ailments are lifestyle disorders. It means that they are prevented and better managed through lifestyle interventions rather than through the use of pharmacological drugs.

It means that there is an urgent need to understand the role of CBD in managing various chronic disorders. However, using health supplements daily is a challenge. On the other hand, consuming CBD as a part of the diet may better manage these conditions.

functional foods and CBD

What Are Functional Foods?

These are food items with health benefits extending beyond their nutritional value. It means that they not only provide energy and vital nutrients to the body but also help prevent and even manage health conditions.

Thus, for example, many spices like turmeric are not only used to color the food, improve its aroma, or for nutritional value, but it also has many other health benefits.

Similarly, CBD is excellent functional food. It mainly means creating products high in nutritional value and having the health benefits of CBD. It could be CBD-infused foods or even food products solely made of various parts of the cannabis plant.

Thus, take the example of hemp seed meal or hemp seed cake. It is what is left of the hemp seed after extracting its oil. However, this hemp cake is rich in vegan proteins, vitamins, and minerals, have small amounts of essential fatty acids and can be readily sourced. If we add CBD to this, we can create a food product that is nutritious and has all the health benefits of CBD.

Another example could be hemp seed oil, healthy oil that is quite rich in omega-3 fatty acids. However, hemp seed oil is naturally CBD-free. But, adding CBD to hemp seed oil would create excellent functional food.

Unlike healthy supplements, functional food is primarily for regular consumption as a part of a regular diet. Thus, for example, one can create smoothies using CBD-infused hemp seed meal or CBD-infused hemp seed oil as a salad dressing.

What Are Some Key Functional Food Benefits?

Functional foods provide many unique benefits over other products like food supplements or natural remedies. Perhaps the biggest advantage is a better nutritional profile and palatability. When consuming functional foods, one does not feel like taking some medicine. Thus, functional foods are easier to add to the daily regime. These foods are consumed just like any other food, and yet they have many health benefits.

When it comes to health benefits, the possibilities are limitless. It is because functional foods are not necessarily made using a single plant extract. Thus, one can add CBD to different healthy foods to create functional foods.

As already mentioned, one can use hemp seed meal with added CBD to make smoothies. One can use it before and after the workout. However, unlike conventional high protein supplements, it would also have the benefits of CBD, which may mean low anxiety, better focus, faster recovery, and the lesser problem of delayed onset muscle soreness (DOMS). It may also mean improved metabolic health and more.

Similarly, using hemp seed oil as a part of the diet is good, as it is quite nutritious. But hemp seed oil with CBD would be even more wonderful.

As already said that one can create even better products by combining different foods. Thus, just think about having CBD-infused multi-fruit juice daily in the morning. This would have all the benefits of multi-fruit juice, along with the health benefits of CBD. Furthermore, one can even fortify this juice with vitamins and minerals to create a highly beneficial and unique offering. Thus, as one can see possibilities here are endless.

CBD and funcional foods

What Are the Stages of CBD-Infused Functional Food Prep?

As the CBD market is quite saturated,  one of the ways of getting into the CBD business is starting with functional foods. Moreover, here the possibilities are almost endless. For example, one may create CBD infused food range focusing on physically active individuals or foods focused on managing certain ailments.

Creating CBD-infused functional food is pretty straightforward. Perhaps the simplest way of starting is just to come up with an idea of some food supplement range and then merely add some CBD to them. These could be food supplements for sports people like vegan protein powders, pre or post-workout shakes, meal replacement plans, and more. Or one can focus on specific disorders like foods for joint health, diabetes, brain health, and more.

Once you have come up with an idea, one of the most important things you need to know is whether your food item is oil-based or water-based. It is vital to know as CBD is naturally fat soluble but is poorly soluble in the water.

Thus, when it comes to adding CBD to oil-based products, it is pretty simple. One can buy CBD wholesale, like CBD isolate or THC-free broad spectrum CBD distillate, and then add these to foods.

However, if you want to create a CBD-infused energy drink, then you would need to use water soluble CBD isolate or water soluble distillate. Unfortunately, there are very few companies in the market like essentiapura that produce water soluble CBD. It is essentially a nano-emulsified liquid concentrate that is ready to add to just any water-based food and has excellent bioavailability.

Additionally, when creating products, one should also think about adding other beneficial ingredients to differentiate the product from the market. For example, a CBD-infused sports drink with curcumin and vitamin Bs reduces post-workout inflammation.

What Is the State of the Functional Food Market in 2022?

It is relatively difficult to say as there is no clear data. Moreover, definitions of functional foods differ globally. However, what we know is that the wellness market is almost $4 trillion, which is massive. Additionally, we know that CBD has been one of the major growth drivers of the functional food market for the last few years.

There are many reasons for the lack of accurate data. Just take an example of fortified juices. Some would say that it is just a food item, another would call it a health supplement, and yet others may classify it as a functional food. Generally, criteria differentiating between foods, functional foods, and healthy supplements vary significantly between the various nations, creating significant challenges.

Nevertheless, it is evident that the CBD market is growing in North America and Europe. Another encouraging point is that the market will continue to grow for a decade or more. The demand for CBD products is continually growing, and the market is still struggling to meet consumer demands. Thus, though the CBD oil market may be much saturated, the market of CBD-infused foods is still nascent and offers many business opportunities.

Top Ways to Boost Functional Food Intake?

If you have decided to get into the functional food segment, there is still lots to think about before launching any food product. One of the ways to start is to identify the segment that one wants to enter. For example, some may come up with a vegan range of products, others foods for brain health, and more.

If you want to know more about ways of boosting functional food intake, it is not very difficult. Here the secret is pretty simple, instead of choosing usual foods, better choose food products with some added health benefits.

Just take an example of dietary oil intake. Everyone consumes oil in one way or another. However, instead of going for regular vegetable oil, one may opt for organic, cold pressed, omega-3 fatty acids rich vegetable oil. If one can find such vegetable oil with CBD, that would be even great.

Similarly, instead of a regular glass of juice in the morning, why not consider multi-fruit juice fortified with vitamins or other beneficial herbs. Thus, such a juice would be not only nutritious but also beneficial to health.

if you are interested in CBD-infused functional foods, we can help you by giving more information.

 

CBD And Your Brain: Everything You Need to Know

It is no secret that cannabis contains mind-altering substances like THC, which can affect brain function. However, there has been growing interest in the non-psychotic cannabinoids in the cannabis plant in recent years. There is a particular interest in the role of cannabidiol (CBD) in brain health.

It is true that CBD is non-psychotic and does not give high or cause euphoria. However, this does not mean that CBD does not influence the brain. On the contrary, studies show that it can affect the working of different brain parts and its action on the brain is quite often opposite to THC.

In fact, most people take CBD due to its impact on the brain. Thus, they use CBD to reduce pain and anxiety, improve sleep, and more. There has been significant interest in its role in reducing epileptic seizures in recent years. Now there is no doubt that CBD may help in epilepsy, and there are even some US FDA-approved CBD-based medications for use in resistant cases of epilepsy.

Moreover, the list of indications for CBD is expanding fast. New studies also show that CBD can help improve mental health and has anti-psychotic effects. Experts are even exploring its role in managing conditions like schizophrenia.

Not only that, but it may also help get rid of substance abuse. It appears that CBD has the potential to help people addicted to cannabis, opioids, alcohol, cocaine, and other substances. Not only that, but it may also help reduce the severity of the withdrawal syndrome.

So, yes, CBD has many effects on the brain, and new neuroimaging techniques and other methods of studying brain function are now helping researchers to understand how CBD works.

CBD for brain health

Does CBD Kill Brain Cells?

No, not in any way. It is a commonly asked question as people know that marijuana has a mind-altering effect and may be somewhat toxic to the brain. However, this has nothing to do with CBD. Moreover, there is sufficient evidence that CBD would not kill brain cells even at extremely high dosages.

In fact, CBD is neuroprotective. Studies show that it can boost the antioxidant capacity of the brain and thus help protect the brain cells. This is the reason why researchers are also exploring its role in managing neurodegenerative disorders like dementia or Parkinson’s. In addition, early studies suggest that CBD may help by protecting brain cells from death.

There is strong evidence from animal studies that CBD does not kill brain cells. Moreover, animal studies allow giving CBD at extremely high dosages. Not only that, in experimental animal studies, researchers can use CBD even in embryos. Thus, a study in an embryo of zebra fish found that a high dosage of CBD did not kill brain cells or cause severe neurotoxicity.

Experts are even exploring CBD use for protecting brain cells from various toxins. Thus, one of the in-vivo studies found that CBD may help protect brain cells from alcohol-induced brain toxicity. Studies show that these effects are mainly due to the antioxidant effect of CBD.

How Does CBD Work in the Brain?

It is one of the complex questions that has been subject to much research. Though research has increased understanding of CBD’s mechanism of action, but it is worth understanding that things are not fully clear. It is quite likely CBD has multiple mechanisms of action, and thus is challenging to know how it works in the brain.

The most well-accepted theory is that it works in the brain due to its impact on the endocannabinoid system. However, again, it is not clear how exactly this enables CBD to influence various brain functions. Though CBD can modulate cannabinoid receptors CB1 and CB2, its action is not very strong.

Researchers think that CBD works by affecting the different types of brain receptors and not just endocannabinoid receptors. Thus, CBD seems to affect serotoninergic, dopaminergic, vanilloid receptor 1 (TRPV1), and more.

CBD also appears to increase the plasma levels of anandamide, which is better known as the “bliss molecule.” Its impact on anandamide levels is believed to help in psychiatric disorders.

Although the mechanism of action of CBD is not fully understood yet, nonetheless, brain imaging studies show that there is a considerable change in the activity of various brain centers after taking CBD. This confirms that CBD can influence brain function in many ways.

CBD and blood brain barrier

Can CBD Cross the Blood Brain Barrier?

Many people are not aware of something called blood brain barrier (BBB). It is a network of closely knitted cells and blood vessels that prevent harmful substances from reaching the brain. BBB is like a dedicated security system of the brain. Thus, it controls the movement of all the substances in and out of the brain. That is why very few infections are able to harm the brain.

But BBB also creates some issues. For example, many medications and supplements cannot penetrate the brain. It means that though these substances may have a beneficial impact on brain health in various experiments, they fail to help in real life.

Fortunately, lipophilic or fat soluble substances have better brain penetration, and CBD is a highly fat soluble substance. Thus, CBD can readily enter the central nervous system (CNS) or cross BBB. That is why it has so many effects on brain cells.

Not only that, it appears that CBD can even reduce inflammation of BBB and thus improve its function. This could be one of the ways in which CBD may exert a protective influence on the brain. Experimental studies suggest that CBD may help in ischemic and inflammatory conditions of the brain. CBD is also good for managing acute traumatic brain injury due to its ability to cross BBB and have a beneficial impact on the BBB.

CBD For Brain Tumors: What’s The Evidence?

Although a lot is known about the influence of CBD on mood and pain, however, in recent years, there has been increasing interest in testing CBD for managing more severe conditions. In addition, interest has been significantly rising in the role of managing brain tumors.

Most brain tumors are glioma. These are cancerous tumors that are very aggressive and difficult to treat. Those diagnosed with the condition have a mean survival of just 14-16 months. Doctors mainly treated it with radiotherapy and chemotherapy, as surgical removal of the tumor is not an option.

CBD will not cure the tumor. However, interestingly enough, evidence is emerging that when it is used along with regular treatment, it may increase lifespan in many instances. For example, in one of the small studies in nine patients, the mean survival rate increased to 22.3 months. This is a considerable increase in the lifespan.

Since very few medications can prolong life in glioma, researchers have wondered about the underlying mechanism of action of CBD. They have proposed that it may be working in many ways. For example, one of the ways CBD helps is by preventing cancer-associated mitochondrial dysfunction, thus preventing the death of brain cells. They think this happens due to the calcium influx induced by CBD through TRPV4 (transient receptor potential cation channel subfamily V member 4) activation.

Studies show that cannabidiol helps in brain tumors in multiple ways, and thus it may help in different kinds of brain tumors. Yet another study demonstrated that CBD might help prevent brain cancer progression by increasing the production of antioxidants in the brain.

CBD also has a supportive role in managing brain tumors

CBD is not just for suppressing the growth of brain tumors. It appears that it can also have a supportive role in treating brain tumors. In addition, it can be a part of palliative care. Thus, regular CBD use may help improve mood, reduce anxiety, and prevent cancer-associated depression. It may also help prevent other issues like pain, nausea, and more.

Another reason for using CBD in brain tumor patients could be to reduce tumor-related seizures. In those living with a brain tumor, these seizures tend to be quite resistant to various treatments. Studies show that CBD could be especially good for those living with resistant seizures. It can help reduce their severity and frequency.

CBD and brain

Are There Any Negative Effects of CBD on The Brain?

Regretfully, very little is known about the negative influences of CBD on the brain, as science still does not have a complete understanding of its mechanism of action. Nevertheless, researchers think that one should not abuse CBD. Furthermore, one should not use CBD for no apparent reason.

Since CBD causes widespread changes in the brain and can affect the working of brain cells, it is quite likely that it may cause neurotoxicity in some. Additionally, it can cause drug-drug interactions, alter the working of the liver, and may have some negative effects on gut health.

To conclude, CBD may not be psychoactive, but it does influence the working of the CNS. It may help reduce activity in hyperactive parts of the brain. Thus, it can help in conditions like anxiety, pain, and mood swings.

It may also help normalize the production of certain neurotransmitters, thus helping in depression. Its ability to change the excitability of neurons can help manage seizures due to epilepsy or brain tumors.

Additionally, new studies show that it can help those diagnosed with brain tumors by extending their lifespan. It has a particular role in the palliative care of brain cancer.

If you are interested in CBD products for brain health, contact us and we can provide more information.

CBD in France: A Market Analysis

France is one of the oldest and most ethnically diverse countries in the EU. It is a nation that has profoundly influenced human civilization through its culture, wine-making, philosophy, arts, music, and politics. It is also one of the most prospective markets for starting any business. Thus, considering France is a must if anyone wants to expand their CBD business in the EU.

France has been initially a bit reluctant to legalize it when it comes to CBD business. There is a cause for concern. France has a significant problem with illegal drugs, and French authorities were worried that CBD might somehow promote the use of illicit cannabis. However, finally, French authorities understand that it is not the case and CBD is a safe and beneficial health product.

First Off, Is CBD Legal in France?

Though there have been many ups and downs in the nation, CBD is finally completely legal in France and has very clear laws.

Like in many nations, the road to CBD legalization in France has not been smooth. France has been quite reluctant to allow broader use of CBD. Initially, it even disapproved of CBD import from other EU member states. Further, France has been slow to allow CBD sales in stores.

In 2019, when the European Commission regularized the CBD market by classifying it as a Novel Food, French authorities remained hesitant. As a result, some individuals got into trouble for importing CBD products. This led to prolonged lawsuits that CBD importers ultimately won. And finally, the highest court in France ruled that people can import and stores can legally sell CBD in the country.

Some of the lawsuits related to the actions of French authorities even reached the European Court, which ultimately helped legalize CBD not only in France but the rest of the EU zone. In addition, the European court ruled that French or other EU member states should not ban the import of CBD products that were legally produced in other member states.

So, now France is fully following the European Commission norms. It means that CBD oil for ingestion must get novel food authorization, and then it can be sold legally in the nation. Authorized or registered CBD products can be sold freely by the stores.

Here it is vital to understand that one can receive novel food authorization in France or even in other EU member states. This means almost no legal hurdles for CBD products legally produced in other EU nations.

When it comes to topical CBD products, they do not need novel food authorization. Similarly, hemp oil is not a novel food and can be readily imported and sold in the nation as a food product.

cbd in france

Can I Bring CBD Into France?

As already mentioned, one can bring CBD into France without any significant issues if the product has been legally produced in other EU member states.

Of course, the product must have undergone novel food authorization by the European Commission’s department of food safety and authority. If one is unsure about what novel food is, one can learn more about it on the website of the European Food Safety Authority (EFSA) website.

From a business point of view, getting this authorization is far easier if the product has been produced in EU nations. However, the procedure is much more complex for those making CBD products outside the EU zone, as there are more significant concerns about the safety and purity of such products.

For those looking to get into the CBD business in France quickly, white-label products from reputed European CBD manufacturers could be an excellent option. It is because such a manufacturer can provide all the necessary advice and documentation needed for the novel food authorization.

CBD Market Analysis: How Does the French Market Stack Up?

France is definitely one of the most attractive markets for healthcare products in the EU zone. If anyone is serious about doing CBD business, France should be on the top of their list. It is one of the biggest CBD markets in the region. Moreover, the acceptability of CBD products in France is excellent.

Although data regarding the CBD market size is still not very reliable, nonetheless, experts estimate that the total CBD market in France stood at about 131 million Euros in 2020. This makes France one of the largest CBD markets in the EU zone, perhaps only next to Germany.

At present French CBD market is dominated by ingestible CBD products, that is, CBD oil and CBD capsules. However, there is a significant market for vaping products, too.

France has dominated the global cosmetics market and fashion industry. Thus, though the CBD cosmetics market in the country is small, it may change considerably in the coming years.

Experts project that the French CBD market will grow at about 250% each year till 2030, which sounds fantastic. Moreover, there is a reason to believe that this trend will continue as France is a 2.5 trillion economy and has a population of above 60 million. Thus, it is one of the most perspective markets for CBD.

france CBD market data

The Top 3 CBD Manufacturers in France

As now the legal status of CBD is clear in France, many companies are jumping into the CBD business in the nation. Some of the CBD producers in the countries are:

NOTO

It is an organization that produces mostly THC-free CBD products. It has quite a diverse range of products, and the company focuses a lot on various health conditions like CBD for improving sleep, helping with menstruation pain pains, post-menopausal syndrome, and more. The company also produces products with added terpenes.

Divie

Yet another budding company with an excellent product range of CBD oil products comes in excellent packing.

Essentia Pura

Yes, we can help start a CBD business in France. We are based in Slovenia. However, Essentia Pura is a pan-European company with extensive experience in assisting businesses that want to enter the CBD business in any part of the world.

Essential Pura can help businesses of any size. We have our own in-house CBD extraction and CBD-based product manufacturing. However, we also produce CBD extraction machines and provide the necessary technology or expertise for startups.

If you are interested in starting a CBD business in France or any part of the world, just contact us.

Minor Cannabinoids: Everything You Should Know

Humans have used cannabis for thousands of years for recreation to industrial use. Besides, they also knew that its extract could help in a range of health conditions.

However, the use of marijuana was suddenly outlawed in most parts of the world by mid-20-century. Regretfully, most countries even banned the cultivation of low THC cultivars. Fortunately, researchers started realizing that not all cannabis products harm health. And some are even quite beneficial.

Despite the ban on recreational use of marijuana in the early to mid of the last century, its medicinal use was allowed. As a result, researchers continued to explore its chemical properties. As a result, they understood that this plant has many unique phytocompounds and more than 100 cannabinoids.

However, despite discovering so many cannabinoids, it would be correct to say that science has been slow to explore the health benefits of various cannabinoids. The popularity of cannabidiol (CBD) has not helped in this direction. In fact, the popularity of CBD had even prevented the study of other cannabinoids.

CBD is undoubtedly among the most abundant cannabinoid, and many of its health benefits are known to science. But now, scientists realize that some unique health effects of cannabis plants are due to the entourage effect that occurs in the presence of other cannabinoids and terpenes in the plant.

minor cannabinoids and health benefits

What Are Minor Cannabinoids?

CBD, THC, and even CBG are in abundance in many cultivars of the cannabis plant, and thus they are called major cannabinoids.

However, there are almost close to 100 known cannabinoids that are very poorly known to science. Nonetheless, things are not that bad, as science now knows the health benefits of tens of these less common cannabinoids.

These cannabinoids are present only in small amounts in the cannabis plant, and thus science calls them minor cannabinoids. However, in the specific cultivars of the cannabis plant, these compounds are more abundant.

There are many ways of getting these minor cannabinoids, like growing cultivars of the cannabis plant in which they are more abundant or using the knowledge of chemistry to change major cannabinoids to minor ones.

There are even some successful attempts at synthesizing these minor compounds. Thus, they are quite likely to become popular in the future, finding broader use as health supplements.

What Are the Types of Cannabinoids?

There are many types of cannabinoids like neutral cannabinoids, cannabinoid acids, varinic cannabinoids, and many other minor cannabinoids.

Though they might belong to different groups; however, the difference is generally minor. Quite often, shared traits are more than differences. It is because they all have a similar beginning. However, even these minor differences in a chemical structure may sometimes result in a considerable change in health benefits.

minor cannabinoid

What Are the Effects of Minor Cannabinoids?

Although there are hundreds of cannabinoids, there we look at some of the more popular ones. About ten of the minor cannabinoids are more or less well studied by science. Rest are still waiting for science to discover their health effects.

Cannabinol

Cannabinol, or CBN, is one of the earliest known cannabinoids that science discovered way back in 1896. It is a result of the degradation of THC under the influence of UV rays. It means that it is more commonly present in plants abundant in THC.

This minor cannabinoid is quite a potent analgesic and also has anti-inflammatory properties. In addition, it is suitable for controlling muscle aches. Science has found it suitable for those living with fibromyalgia in recent years.

Additionally, it is suitable for modulating immunity, reducing the risk of various allergies. Finally, studies show that it is also ideal for controlling glaucoma.

When it comes to metabolic effects, it seems to stimulate appetite.

It is suitable for reducing anxiety, promoting relaxation, and improving sleep quality.

Cannabichromene

Cannabichromene or CBC is in abundance in some cannabis cultivars. It appears to have a greater affinity for CB2 receptors than CB1, which means that it affects peripheral organs more than the brain.

Some researchers have studied it for its anti-inflammatory action. In animal studies, it seems to be as good as some of the commonly used medications but without their side effects.

Science has also explored its ability to reduce neurodegeneration, which may be associated with its anti-inflammatory action. Additionally, it seems to stimulate neural stem progenitor cells and thus have a beneficial effect. It may also help in neurodegeneration by modulating the brain’s immune cells and astrocytes. It is quite likely to be good for preventing and managing Alzheimer’s.

Cannabigerol

Cannabigerol or CBG is a precursor of THC and CBD, meaning that these well-known major cannabinoids are formed in the plant through the conversion of CBG. However, as the plant matures, CBG levels decrease. It also means that it has the properties of influencing both the CB1 and CB2 receptors.

It appears to be especially good for reducing inflammation. Researchers have paid particular attention to its role in managing inflammatory bowel disease (IBD), especially Crohn’s disease. It may help prevent its exacerbation and help maintain its prolonged remission. It appears to help in multiple ways, from reducing inflammation and boosting NO production to helping fight oxidative stress.

Since it is so good for reducing inflammation, it is also beneficial for brain health and may have a role in neurodegenerative disorders. Additionally, it also demonstrated anti-cancer activity in many experimental studies. It may suppress the growth of cancer cells and reduce the risk of metastasis.

Cannabidioloic Acid

Cannabidioloic Acid, or CBDA, has a low affinity for CB1 or CB2 receptors, but it may act on other pathways, including the serotoninergic pathway. Due to its impact on various inflammatory enzymes, it is especially good for reducing pain and inflammation. CBDA is especially good for preventing hyperalgesia or increased pain sensation found in conditions like fibromyalgia.

CBDA also has a potent nausea-reducing effect, which is much stronger than CBD. In addition, it appears to suppress acute nausea quite well and thus can be part of anti-cancer treatment.

Further, some experts suggest that it may be more effective than CBD in controlling seizures. Thus, it is better for those living with conditions like resistant epilepsy.

Cannabigerolic Acid

CBGA is the father of all major cannabinoids that is THC and CBD. It is especially good for those living with metabolic disorders and it may help prevent cardiovascular issues. Studies show it to be good for reducing insulin resistance. In addition, some studies suggest that it is good for relieving nausea and preventing vomiting.

Researchers are also exploring its role in cancer prevention. For example, it may help prevent certain types of cancers like colon cancer and even leukemia.

Tetrahydrocannabinolic Acid

Tetrahydrocannabinolic Acid, or THCA, is the father of THC. However, it is non-psychotic and thus safe to use for health benefits. In recent years, science has explored its anti-inflammatory action. It appears to be quite good for reducing inflammation caused by various disorders. It is not only good for local inflammation but also systemic inflammation. Thus, for example, one study shows that it may have a role in managing inflammatory conditions like COPD.

Science is also exploring many other amazing effects of this minor cannabinoid-like anti-inflammatory activity and its role in preventing dementia. It may also help prevent seizures and help reduce rigidity in Parkinson’s.

Cannabidivarin

Cannabidivarin or CBDV is suitable for managing seizures due to its impact on various brain centers. As a result, in recent years, it has gained significant attention for treating epilepsy, and many pharmaceutical companies are testing it to manage the condition. At least, early results are highly encouraging, and CBDV-based medications to treat epilepsy may likely get an FDA nod soon.

It is also suitable for other brain disorders like autism spectrum disorders. In addition, it may have a role in managing multiple sclerosis and even in rare conditions like Duchenne muscular dystrophy (DMD).

Tetrahydrocannabivarin

THCV is good for reducing inflammation, though at present most of the evidence comes from studies in mice. It also showed some promise in managing epilepsy. Additionally, it can help lower blood glucose levels. Some studies have also explored its role in various skin disorders.

One interesting fact to note about THCV is that studies seem to suggest that it is a negative modulator of the endocannabinoid system, which is just the opposite of what major cannabinoids like THC or CBD do. So, it means that it may have a role in managing substance abuse and reducing the side effects of marijuana.

This is undoubtedly not a complete list of all the minor cannabinoids. This discussion only demonstrates how various cannabinoids differ from each other. Exploring the role of each cannabinoid may help create unique health supplements and even medications. In many cases, these remarkable compounds may even help treat some rare disorders like muscular dystrophies or multiple sclerosis.

There are many other minor cannabinoids that science is studying, like Cannabitriol, Cannabicitran, delta-8 THC, and more. What is interesting is how diverse these cannabinoids are in their health effects. Some may boost the function of CBD or THC, others modulate their health effects, while some may even act as antagonists of these well-known major cannabinoids.

To conclude, science has paid much attention to CBD and even THC in the last few decades. However, studies indicate that many minor cannabinoids also possess amazing health effects. Thus, it is now time for science to start exploring these minor cannabinoids and studying how various cannabinoids interact with each other. As we explore these minor constituents of cannabis, we are pretty likely to find some compounds with unique health effects.

If you are interested in learning how minor cannabinoids can help you create unique products, contact us, we would be happy to help you out.

CBGA (Cannabigerolic Acid) What It Is, Uses & Benefits

The cannabis plant is not just about cannabidiol (CBD). CBD is just one of the most abundant cannabinoids. Even cannabis experts of 20-century knew that there are many other cannabinoids. And researchers could discover many of them in the mid of the last century.

Any plant contains thousands of organic compounds that work in sync with each other, providing nutrients and health benefits. But, since plants are so complex, identifying the beneficial compounds is challenging even for modern science.

The list of identified organic compounds mostly unique to the cannabis plant is expanding fast. New studies could identify more than 500 beneficial compounds and above 100 cannabinoids in the plant.

Understanding various cannabinoids is vital, considering that they have different biological effects. However, what has amazed researchers those various cannabinoids not only have different health effects, but they can often have just an opposing action on the human body.

CBGA molecular structure

What is CBGA?

CBGA is one of the non-psychotic cannabinoids in the cannabis plant. Researchers have identified more than 100 cannabinoids in cannabis or hemp plants, but there is something unique about CBGA.

CBGA is unique in the way that it is a precursor to all other cannabinoids. It means that it gets converted to all other cannabinoids in the plant, including CBD and THC. It also means that it is regularly produced in the plant in small amounts for later transformation into other compounds.

CBDA and CBGA: What’s the Difference?

To understand the difference in a simple term, CBGA is the grandfather of all cannabinoids, and CBDA is the father of CBD.

In the hemp plant, enzymatic activity converts CBGA to CBDA (Cannabidiolic acid), CBCA (cannabichromenic acid), and THCA (tetrahydrocannabinolic acid). Therefore, it means that CBD, CBC, and THC are the outcome of enzymatic conversion of CBDA, CBCA, and THCA, in hemp or cannabis plant.

Thus, various enzymes convert CBGA to different cannabinoids, including CBDA. Although CBDA is related to CBGA, it is chemically different, and it also means different health benefits.

It is worth understanding that science is still exploring the health benefits of non-CBD cannabinoids. Studies show that even a tiny change in the chemical structure of any cannabinoid may significantly alter its role in the human body.

However, the complex is to understand the interaction of various cannabinoids to demystify the “entourage effect.” Researchers know that taking multiple cannabinoids is more beneficial. But they do not understand how different cannabinoids potentiate the action of each other.

CBGA Effects: How Does It Feel?

CBGA is a non-psychotic. It means that a person using it would not get high. However, it does not mean that it would not have any impact on the brain. It only means that it would have mild action on the brain that would be pleasant, relaxing, and perhaps pain relieving.

It may also help lower stress levels and anxiety, reduce nausea, and help a person feel fresh. So, it would provide relief due to its impact on CB1 receptors in the brain and its effect on CB2 receptors in other body parts.

CBGA benefits

CBGA Benefits for The Human Body

Although CBGA is less studied by science than CBD, nevertheless, there are many studies indicating that it may help in various ways. In addition, some of the experience regarding its health benefits come from the use of broad-spectrum CBD. Thus, it is good to use alone or in combination with CBD.

Diabetes & Heart health

It is no secret that there is a strong association between diabetes and vascular diseases. Studies show that CBGA can inhibit an enzyme called aldose reductase, and thus help reduce glucose levels in the body. It also has a positive impact on lipid profile.

CBGA is not very harsh, and most of its actions are mild. Thus, do not expect to lower glucose immediately with CBGA. However, its prolonged and continuous use would help gain better control over blood glucose and improve lipid profile. Moreover, it has an excellent safety profile.

Further, studies show that it may help with diabetes or metabolic disorders due to its ability to modulate receptors called PPAR. These receptors play an important role in cellular metabolism, and their dysfunction is associated with the development of insulin resistance and diabetes.

It May help control epilepsy

The role of cannabinoids in controlling epilepsy has become a subject of high interest in recent years. It happened due to the approval of a CBD-based drug by the US FDA and EMA. Now researchers know that they are treading the right path. They understand that many benefits of hemp extracts are due to lesser-known cannabinoids.

Like other cannabinoids, researchers are testing CBGA for its anticonvulsant properties, and the initial results are highly encouraging. Early studies show that CBGA is undoubtedly one of the cannabinoids good for reducing convulsions in epilepsy. There is strong evidence from earlier animal studies that it works.

Other health effects

Despite its discovery more than half a century back, there is still limited research into its health benefits. It is because most cannabis research stopped for most of the second half of the 20th century. However, new studies indicate that it is suitable for reducing inflammation, pain, and stress and has many other benefits.

From CBGA to CBG: What’s The Process?

As CBGA is the father of all cannabinoids, it is possible to convert it into other cannabinoids like cannabigerol (CBG). In some cases, this conversion may require the use of specific enzymes; in other instances, just an application of heat.

CBGA is pretty simple to convert to CBG through heat application which results in the decarboxylation of CBGA and formation of CBG. CBG is no longer an acid. CBG is of particular interest due to its opposing action to THC.

Thus, CBG antagonizes CB1 receptors in the brain, unlike THC. This opposing action means that it may play a role in managing marijuana addiction and other substance abuse disorders. Additionally, it also appears to affect adrenergic receptors and serotonergic receptors and thus help prevent mood disorders and other brain issues. It is also suitable for reducing inflammation.

To conclude, science has developed a sufficient understanding of CBD, and now is the right time to start exploring other cannabinoids in cannabis or hemp plant. Further, there is a need to understand how they interact with CBD and explore their health benefits.

If you are interested in exploring the power of CBD, understand what products are right for you? Just ping us.